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Coil–globule transition : ウィキペディア英語版 | Coil–globule transition
In polymer physics, the coil–globule transition is the collapse of a macromolecule from an expanded coil state through an ideal coil state to a collapsed globule state, or vice versa. The coil–globule transition is of importance in biology due to the presence of coil-globule transitions in biological macromolecules such as proteins and DNA. It is also analogous with the swelling behavior of a crosslinked polymer gel and is thus of interest in biomedical engineering for controlled drug delivery. A particularly prominent example of a polymer possessing a coil-globule transition of interest in this area is that of Poly(N-isopropylacrylamide)(PNIPAAm). ==Description==
In its coil state, the radius of gyration of the macromolecule scales as its chain length to the three-fifths power. As it passes through the coil–globule transition, it shifts to scaling as chain length to the half power (at the transition) and finally to the one third power in the collapsed state.〔(【引用サイトリンク】url=http://physchem.ox.ac.uk/~doye/jon/papers/homop/node8.html )〕 The direction of the transition is often specified by the constructions 'coil-to-globule' or 'globule-to-coil' transition.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Coil–globule transition」の詳細全文を読む
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